A Derry, New Hampshire native, Segreti gained over 1,100 yards as a sophomore, being selected as MVP of both the homecoming game (Turco award) and the Parents Weekend game (Anderson award) vs. Lehigh when he ran for 105 yards in one quarter of play. Later that season, he gained over 150 yards vs. Brown to take the national lead in touchdowns in Division I-AA. He earned first team All New England, second team All East and honorable mention All-American honors.
As a junior (1989 season) he was again first team All New England, a Patriot League All-Star and honorable mention All-American, running for 1,099 yards and 12 touchdowns in 11 games. In the Parents Weekend game that year, he won a second Anderson award as the MVP, gaining 111 yards in 23 attempts.
He capped his career with a strong senior season, being chosen first team All-New England, first team Patriot League, first team All-East and first team Football Gazette All-American. He also became the first two-time winner of the Turco award. Segretti also had the distinction of being selected as the Patriot League’s Most Valuable Player in 1990 and he was the first player to be chosen for the Davitt award as the teams' outstanding back in three seasons (1988, 1989 and 1990).
He graduated as the second leading ground gainer in Crusader history with 3,461 yards, while he graduted as the HC career leader in 100 yard games in a career (20) and tied the record for 100 yard games in a season (seven in 1989 and 1990).
He competed on team that compiled an overall record of 39-4-1, three of those teams having been crowned Patriot League Champions and two of which (1987 and 1989) were selected “ECAC I-AA Team of the Year”.